GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs875971 | 1 | rs4718307 | chr7:65610988 | LOC729156 | chr7:66274980-66309813:- | -0.16 | -3.47 | 0.000572 | Aortic root size |
| THCA | cis | rs875971 | 1 | rs4718307 | chr7:65610988 | RABGEF1 | chr7:66093890-66276446:+ | -0.66 | -14.15 | 3.08E-38 | Aortic root size |
| THCA | cis | rs2243480 | 1 | rs4718309 | chr7:65627764 | CCT6P1 | chr7:65216092-65228661:+ | -0.42 | -6.7 | 5.9E-11 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718309 | chr7:65627764 | CRCP | chr7:65579805-65619551:+ | 0.3 | 4.63 | 4.66E-6 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718309 | chr7:65627764 | LOC493754 | chr7:65993446-66057363:- | -0.29 | -3.36 | 0.000833 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718309 | chr7:65627764 | RABGEF1 | chr7:66093890-66276446:+ | -0.57 | -7.14 | 3.42E-12 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718315 | chr7:65648541 | CCT6P1 | chr7:65216092-65228661:+ | -0.42 | -6.7 | 5.9E-11 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718315 | chr7:65648541 | CRCP | chr7:65579805-65619551:+ | 0.3 | 4.63 | 4.66E-6 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718315 | chr7:65648541 | LOC493754 | chr7:65993446-66057363:- | -0.29 | -3.36 | 0.000833 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718315 | chr7:65648541 | RABGEF1 | chr7:66093890-66276446:+ | -0.57 | -7.14 | 3.42E-12 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718316 | chr7:65648731 | CCT6P1 | chr7:65216092-65228661:+ | -0.42 | -6.7 | 5.9E-11 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718316 | chr7:65648731 | CRCP | chr7:65579805-65619551:+ | 0.3 | 4.63 | 4.66E-6 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718316 | chr7:65648731 | LOC493754 | chr7:65993446-66057363:- | -0.29 | -3.36 | 0.000833 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718316 | chr7:65648731 | RABGEF1 | chr7:66093890-66276446:+ | -0.57 | -7.14 | 3.42E-12 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718317 | chr7:65648901 | CCT6P1 | chr7:65216092-65228661:+ | -0.41 | -6.63 | 9.28E-11 | Diabetic kidney disease |